How do you handle deployments and redeployments?

I'm wondering what the best way is to handle installs\reinstalls of DLP (12.0) onto our associate population.  We seem to be having an issue with our current package where it will install and somehow uninstall itself. 

We use SCCM as our main distribution of the software and I was wondering what experieces others have had when deploying.  What type of executable did you run, where there scripts involved?

Thank you for any answers provided.